Bridging anticoagulation therapy

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Periprocedural bridging management of anticoagulation.

More than 2.5 million Americans are chronically anticoagulated for indications including venous thromboembolism (VTE), mechanical heart valve(s), or atrial fibrillation (AF).1 Each year, 10% of these patients require temporary interruption of anticoagulation for an invasive procedure. Defining the most appropriate management strategy for these patients requires an assessment of the periprocedur...

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Oral anticoagulation with a vitamin K-antagonist requires special consideration when surgery or interventional procedures are planned. This is mainly due to the half life of vitamin K-antagonists and to the need for safe and effective anticoagulation prior to and during surgery as well as in the postoperative period. So far, the continuous infusion of unfractionated heparin (UFH) has been the m...

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Perioperative Bridging Anticoagulation Unhelpful for Invasive Procedures.

Bottom Line Bridging anticoagulation worsens outcomes for patients with atrial fibrillation who undergo an elective invasive procedure, resulting in more episodes of major bleeding and no difference in the rate of stroke or venous thromboembolism. Most of the patients in the study had a CHADS2 score of 1 (23%), 2 (40%), 3 (24%), or 4 (10%). The patients were largely undergoing minor surgical pr...

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Bridging therapy for oral anticoagulation increases the risk for bleeding-related complications in total joint arthroplasty

BACKGROUND Patients scheduled for elective surgery with a high risk of thromboembolism require anticoagulation bridging therapy perioperatively. The purpose of this study was to assess the risk of thromboembolic events and bleeding-related complications after total hip and knee arthroplasty in patients requiring bridging therapy for anticoagulants. METHODS A retrospective cohort study of all ...

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ژورنال

عنوان ژورنال: Cor et Vasa

سال: 2018

ISSN: 0010-8650,1803-7712

DOI: 10.1016/j.crvasa.2018.04.002